Description
What it is
Cagrilintide (research alias AM833) is a synthetic 37-residue amylin-analogue peptide. Its structure carries a single intramolecular disulfide loop near the N-terminus, an amidated C-terminus, and N-terminal acylation with a long fatty diacid attached through a glutamic-acid spacer, a modification that promotes reversible binding to serum albumin. Reported molecular formula C194H312N54O59S2, average mass approximately 4409 g/mol, CAS 1415456-99-3. Typically supplied as the acetate salt.
Research context
The molecule is stocked as a reference-grade reagent for in-vitro characterisation of the amylin and calcitonin receptor family and related molecular metabolic-signalling work by qualified laboratory professionals. It is of interest for its lipidation chemistry and its long circulating profile in the published literature. Nothing here constitutes a protocol, indication or claim of effect.
93 studies indexed on PubMed (NIH) for Cagrilintide as of August 2026. A measure of research volume only, not a claim of efficacy.
Handling and storage
Supplied lyophilised in a sealed vial. For laboratory handling the powder is reconstituted with bacteriostatic or sterile water; this is a handling note, not a dose. As a disulfide-bearing, acylated peptide it is sensitive to oxidation, light and repeated freeze-thaw, so store the lyophilised powder cold and keep any reconstituted material cold and short-lived.
Testing and quality
Every batch is third-party tested. The certificate of analysis states the salt form, reports HPLC purity with chromatogram and confirms identity by mass spectrometry (expected versus observed mass near 4409). Supplied for laboratory research use only. Not for human or animal consumption.
Specification
Frequently asked questions
Research handling and related compounds
New to handling lyophilised material? See our reconstitution guide, the storage and shelf-life guide, and how to read a Certificate of Analysis.
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