Description
What it is
Sema is a synthetic acylated research peptide supplied as a lyophilised powder for laboratory use. Its structure carries a non-coded amino-acid substitution that improves resistance to enzymatic cleavage, along with a long-chain fatty-diacid modification attached through a spacer, a feature that promotes reversible binding to serum albumin. Typically supplied as the acetate salt. This listing is a chemical reagent description only, and refers to no medicine, indication or effect.
Research context
Sema is stocked as a reference-grade peptide for in-vitro characterisation and analytical method development by qualified laboratory professionals. For an acylated peptide of this kind, identity rests on the supplier’s analytical package, since a purity figure alone does not confirm the molecule.
5404 studies indexed on PubMed (NIH) for Sema as of August 2026. A measure of research volume only, not a claim of efficacy.
Handling and storage
Supplied lyophilised in a sealed vial. For laboratory handling the powder is reconstituted with bacteriostatic or sterile water; this is a handling note, not a dose. Store the lyophilised powder cold and protected from light, avoid repeated freeze-thaw, and keep any reconstituted material cold and short-lived.
Testing and quality
Every batch is third-party tested. The certificate of analysis states the salt form, reports HPLC purity with chromatogram and confirms identity by mass spectrometry, expected versus observed mass. Supplied for laboratory research use only. Not for human or animal consumption.
Specification
Frequently asked questions
Research handling and related compounds
New to handling lyophilised material? See our reconstitution guide, the storage and shelf-life guide, and how to read a Certificate of Analysis.
Related research compounds in GLP-1: Tirz, Reta, Cagrilintide.
Further reading: GLP-1 dual and triple agonists.





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