Description
What it is
MT-II is a synthetic cyclic heptapeptide, a structural analogue of alpha-melanocyte-stimulating hormone. Its sequence carries an N-terminal acetyl group, a norleucine residue and a lactam ring closed between aspartate and lysine, terminating in a C-terminal amide. The molecular formula is C50H69N15O9 with a free-base mass of about 1024.2 g/mol, and it carries the CAS number 121062-08-6. The C-terminal amide is the key structural marker that distinguishes MT-II from the closely related free-acid peptide, which differs by only around 1 Da and shares the same ring, so both HPLC and mass spectrometry are needed to confirm identity.
Research context
MT-II is offered strictly as a chemical reference material for in-vitro laboratory research by qualified professionals, for example in receptor-binding and analytical method work on melanocortin-class peptides. No use in or on humans or animals is intended, described or supported. This is a research chemical and is not for human use.
242 studies indexed on PubMed (NIH) for MT-II as of August 2026. A measure of research volume only, not a claim of efficacy.
Handling and storage
Supplied as a lyophilised powder. For research handling the powder is reconstituted with bacteriostatic water; store the lyophilised material cold and protected from light, and treat any reconstituted solution as cold-chain dependent and short-lived.
Testing and quality
Supplied with a Certificate of Analysis stating salt form and residual solvent, HPLC purity with chromatogram and mass spectrometry confirmation, which matter here because of the near-identical partner peptide. Supplied for laboratory research use only. Not for human or animal consumption.
Specification
Frequently asked questions
Research handling and related compounds
New to handling lyophilised material? See our reconstitution guide, the storage and shelf-life guide, and how to read a Certificate of Analysis.
Related research compounds in Skin & Cosmetic: GHK-Cu.
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