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For laboratory research use only. Not for human consumptionEvery vial: QR to its own batch certificateUK-registered · third-party tested

Thymosin Alpha-1

Research use only · not for human consumption

Thymosin alpha-1 (thymalfasin, Talpha1) is a 28-residue N-acetylated peptide, C129H215N33O55, studied as a reference immunomodulatory peptide. Supplied as a lyophilised research reagent with a Certificate of Analysis, for laboratory research use only. Not for human or animal consumption. Read the research on Thymosin Alpha-1 →

£55.00
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SKU: AXN-THYMOSIN-A1
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Description

✓ Per-batch CoA✓ QR-to-CoA on vial✓ HPLC + MS (Janoshik)✓ Same-day UK dispatch

What it is

Thymosin alpha-1 (Talpha1, also known as thymalfasin) is a 28-amino-acid peptide with a naturally acetylated N-terminus, generated in the body by cleavage of the larger precursor prothymosin alpha. The sequence is Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN. It is highly acidic, rich in aspartate and glutamate, and contains no cysteine, so there are no disulfide bridges. The molecular formula is C129H215N33O55 with a free-base mass of about 3108.3 g/mol, and it carries the CAS number 62304-98-7. The N-acetyl group is part of the authentic molecule and should be confirmed rather than assumed.

Research context

Thymosin alpha-1 is studied in vitro as a reference immunomodulatory peptide, for example in Toll-like receptor 9 and dendritic-cell signalling assays and T-cell differentiation research. It is supplied here strictly as a laboratory reagent for such investigational work by qualified professionals.

Research activity data from NIH

580 studies indexed on PubMed (NIH) for Thymosin Alpha-1 as of August 2026. A measure of research volume only, not a claim of efficacy.

Handling and storage

Supplied as a lyophilised powder. For research handling the powder is reconstituted with bacteriostatic water; store the lyophilised material cold and protected from light and moisture, and treat any reconstituted solution as cold-chain dependent and short-lived. As a cysteine-free peptide it has no oxidation-sensitive disulfide.

Testing and quality

Supplied with a Certificate of Analysis confirming the N-terminal acetylation and observed mass near 3108, HPLC purity with chromatogram and mass spectrometry, and ideally an endotoxin note. Supplied for laboratory research use only. Not for human or animal consumption.

Specification

PubChem CID (NIH)16130571
SEQUENCEAc-SDAAVDTSSEITTKDLKEKKEVVEEAEN (28 aa, N-terminally acetylated)
MOLECULAR FORMULAC129H215N33O55
MOLECULAR WEIGHT3108.3 g/mol
CAS NUMBER62304-98-7
PURITY>=98% (HPLC)
FORMLyophilised powder
APPEARANCEWhite to off-white lyophilised powder
SHELF LIFE36 months at -20 C, sealed
RECONSTITUTION STABILITYUse within 2 to 4 weeks at 2 to 8 C after reconstitution

Frequently asked questions

What is Thymosin Alpha-1?
What it is
Thymosin alpha-1 (Talpha1, also known as thymalfasin) is a 28-amino-acid peptide with a naturally acetylated N-terminus, generated in the body by cleavage of the larger precursor prothymosin alpha. Supplied lyophilised for laboratory research only.
What does the research say about it?
580 studies indexed on PubMed (NIH). We link the live record so you can review it. No health claims are made.
Is Thymosin Alpha-1 legal to buy in the UK for research purposes?
Yes. Not a licensed medicine; supplied as a research chemical for laboratory research use only, to researchers aged 18+. Not for human or veterinary use.
How do I reconstitute it?
Reconstitute with bacteriostatic water; the volume added sets the concentration. See our reconstitution guide. No dosing guidance is provided.
What testing has been done on this product?
Third-party tested (Janoshik): HPLC purity with chromatogram and mass-spec identity, per-batch Certificate of Analysis, QR code on the vial linking to it.
How should I store it and what should it look like?
Store cold and dark (−20 C long term); keep any reconstituted solution refrigerated. A white to off-white lyophilised powder is normal, giving a clear colourless solution once reconstituted.

Research handling and related compounds

New to handling lyophilised material? See our reconstitution guide, the storage and shelf-life guide, and how to read a Certificate of Analysis.

Additional information

Strength

10 mg

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