Description
What it is
Selank, also coded TP-7, is a synthetic heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP) and a free-base molecular weight of roughly 751.9 g/mol. It is an analogue of the natural immunomodulatory tetrapeptide tuftsin, extended with a C-terminal Pro-Gly-Pro cap. That proline-rich tail is a stabiliser: it protects the tuftsin core from rapid peptidase degradation. The molecule carries basic lysine and arginine residues, no cysteine and no disulfide bond. AxYn supplies it as 5 mg and 10 mg research vials, commonly as the acetate salt.
Research context
Selank is studied at the receptor and molecular level. Preclinical work describes positive modulation of GABAergic signalling, effects on BDNF expression, and modulation of the enkephalin system through inhibition of enkephalin-degrading enzymes, alongside immunomodulatory activity inherited from its tuftsin origin. It is used strictly as a reference peptide for in-vitro research by qualified professionals.
68 studies indexed on PubMed (NIH) for Selank as of August 2026. A measure of research volume only, not a claim of efficacy.
Handling and storage
Supplied lyophilised. For laboratory handling the powder is reconstituted with bacteriostatic water. Store the lyophilised vial cold, around minus 20C, desiccated and protected from light. Reconstituted solution is cold-chain dependent and light-sensitive.
Testing and quality
Every batch is third-party tested. The Certificate of Analysis should state the salt form, HPLC purity with chromatogram, and mass spectrometry confirming the expected 751.9 mass, which also distinguishes Selank from the related peptide Semax. Supplied for laboratory research use only. Not for human or animal consumption.
Specification
Frequently asked questions
Research handling and related compounds
New to handling lyophilised material? See our reconstitution guide, the storage and shelf-life guide, and how to read a Certificate of Analysis.
Related research compounds in Cognitive, Mood & Sleep: Semax, DSIP.
Further reading: Semax vs Selank.


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