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For laboratory research use only. Not for human consumptionEvery vial: QR to its own batch certificateUK-registered · third-party tested

TB-500

Research use only · not for human consumption

TB-500 is a peptide related to Thymosin beta-4, supplied as the Ac-LKKTETQ fragment or full-length Tb4 with the molecule stated on the Certificate of Analysis. Lyophilised, third-party tested. For laboratory research use only. Not for human or animal consumption. Read the research on TB-500 →

Price range: £30.00 through £48.00
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SKU: AXN-TB-500
Category: ,

Description

✓ Per-batch CoA✓ QR-to-CoA on vial✓ HPLC + MS (Janoshik)✓ Same-day UK dispatch

What it is

TB-500 is a market name used for material related to Thymosin beta-4 (Tb4). It refers to either the short synthetic fragment Ac-LKKTETQ (Thymosin beta-4 residues 17 to 23, N-acetylated, roughly 889 g/mol) or the full 43-residue Thymosin beta-4 protein (C212H350N56O78S, about 4963 g/mol). Because the two molecules differ by more than fivefold in mass, the actual sequence in a given vial must be confirmed rather than assumed from the name alone.

Research context

In the published literature Thymosin beta-4 is characterised as the major intracellular G-actin-sequestering peptide, with the LKKTETQ region mediating the actin interaction that regulates cell migration. Reported research activity spans actin dynamics, endothelial cell migration and angiogenesis in preclinical models. This listing describes the molecule for laboratory investigation only and makes no claim of any effect in humans or animals.

Research activity data from NIH

24 studies indexed on PubMed (NIH) for TB-500 as of August 2026. A measure of research volume only, not a claim of efficacy.

Handling and storage

Supplied lyophilised for reconstitution with bacteriostatic water as a research-handling step. Store the lyophilised powder cold and protected from light; reconstituted peptide is less stable and cold-chain dependent. The full-length protein contains a single methionine, so oxidation is a degradation route worth monitoring.

Testing and quality

Every batch is third-party tested. Because TB-500 is an identity trap, the Certificate of Analysis states the actual molecule (fragment versus full Tb4), the sequence, HPLC purity with chromatogram and mass-spectrometry identity (expected versus observed mass).

Supplied for laboratory research use only. Not for human or animal consumption.

Specification

PubChem CID (NIH)62707662
SEQUENCEAc-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ)
MOLECULAR FORMULAC38H68N10O14 (acetylated fragment)
MOLECULAR WEIGHT889 g/mol (acetylated fragment)
CAS NUMBERAvailable on the Certificate of Analysis
PURITY>=98% (HPLC)
FORMLyophilised powder
APPEARANCEWhite to off-white lyophilised powder
SHELF LIFE36 months at -20 C, sealed
RECONSTITUTION STABILITYUse within 2 to 4 weeks at 2 to 8 C after reconstitution

Frequently asked questions

What is TB-500?
What it is
TB-500 is a market name used for material related to Thymosin beta-4 (Tb4). Supplied lyophilised for laboratory research only.
What does the research say about it?
24 studies indexed on PubMed (NIH). We link the live record so you can review it. No health claims are made.
Is TB-500 legal to buy in the UK for research purposes?
Yes. Not a licensed medicine; supplied as a research chemical for laboratory research use only, to researchers aged 18+. Not for human or veterinary use.
How do I reconstitute it?
Reconstitute with bacteriostatic water; the volume added sets the concentration. See our reconstitution guide. No dosing guidance is provided.
What testing has been done on this product?
Third-party tested (Janoshik): HPLC purity with chromatogram and mass-spec identity, per-batch Certificate of Analysis, QR code on the vial linking to it.
How should I store it and what should it look like?
Store cold and dark (−20 C long term); keep any reconstituted solution refrigerated. A white to off-white lyophilised powder is normal, giving a clear colourless solution once reconstituted.

Research handling and related compounds

New to handling lyophilised material? See our reconstitution guide, the storage and shelf-life guide, and how to read a Certificate of Analysis.

Related research compounds in Recovery & Repair: ARA-290, KPV, BPC-157.

Further reading: BPC-157 vs TB-500.

Additional information

Strength

5 mg, 10 mg

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